What substance was originally used to treat gonorrhoea but is now less effective due to resistance?

Penicillin was originally used as an effective treatment for gonorrhoea, a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. Over the years, widespread use of penicillin led to the development of antibiotic resistance in these bacteria. This means that the bacteria have evolved to survive despite the presence of penicillin, making the drug less effective in treating the infection.

As resistance has increased, medical professionals have had to turn to other antibiotics in an effort to combat gonorrhoea. The emergence of multi-drug resistant strains has also complicated treatment options, highlighting the importance of appropriate antibiotic use and monitoring resistance patterns. This situation underscores the challenges faced in infectious disease management and the ongoing need for research into new treatments.

Other substances listed, such as ibuprofen, Advil (which is just a brand name for ibuprofen), and aspirin, are mainly used for pain relief and inflammation management and do not have efficacy against bacterial infections like gonorrhoea.